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pentobarbital will reduce the extent or effect of tamoxifen by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Watch.pentobarbital will lower the extent or result of eletriptan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.Many individuals also reach for over-the-counter sleep aids, for example melatonin. O